Milton Rocha Cirurgia Plástica e Reconstrutiva em Recife - Pernambuco


Botox, Toxina Botulínica


The aging process of the skin comprehends physiologic alterations, caused by many factors, including: age, genetic heritage, exposure to external agents such as the sun, pollution, inappropriate diet, and stress. Adding to those factors, the constant muscular activity that is necessary to different facial expressions, throughout the years, form the expression lines, or wrinkles.

The first areas of the face where you can see them are the frontal region, procerus, eyebrow corrugator, eye orbicular. Besides having a negative influence on the appearance, the expression wrinkles, when located on the frontal and glabella regions, give the person an angry or worried look.

The Botulinic Toxin is a natural medicine that has been used in Medicine for many years. To obtain it, it’s necessary to have highly sophisticated technology to control the bacteria Clostridium botulinum (which produces the toxin), until its purification and lyophilization phases, resulting in a complex protein, stabilized with sodium chloride, serum albumin, and sterilized. This substance promotes a neuropathic blockage, that is, it blocks the release of acetylcholine (substance which produces the stimulus from the nerve to the muscle). That way, there is NO muscular contraction to generate wrinkles.


It is recommended to treat dynamic wrinkles, that is, wrinkles that appear from repetitive action from the muscles of the face. It is recommended for patients with frontal wrinkles, glabella (between the eyebrows), and periorbital (crow’s feet). It can still be applied in other areas of the face, however with more limited results. This procedure produces small swelling, and it requires special care during the first hours.


With a syringe (4ml), the doctor takes the diluent (SF ,9%) and carefully introduces it on a vial with Botulinic Toxin. After the dilution, the antisepsis (cleaning) is made on the area to be treated, and then the Botulinic Toxin is injected on the region near the eyes (to treat “crow’s feet”) and above the eyebrows (to treat the wrinkles of the forehead and between the eyebrows). The dose varies from 10 to 20 units per area, with a maximum total of 50 UI per patient.


After the application, it takes up to 72 hours for the total blockage of the receptors, and depending on the dosage, it can last from 4 to 6 months. When used in therapeutic dosages, the effect will only remain on the treated area, and it will progressively lose its effect.


  • Hypersensitivity to any components of the formula (Albumin and the Toxin);
  • Patients with needle intolerance;
  • Pregnant or breastfeeding women;
  • Patients using aminoglykosides (antibiotics);
  • Patients with inflammatory reactions of infections on the regions to be treated;
  • Patients with wrinkles purely due to sun exposure.

To know more about Botulinic Toxin, call (81) 3019 0909 and schedule an appointment.


  • Filling
    It fills facial wrinkles,
    natural creases, and lips. [...]
  • Peeling
    Reversion of alterations such as spots, wrinkles,
    elasticity, renewing the aspect of the skin. [...]

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